Research Areas

A combination of molecular, cellular and integrative method to investigate the nervous system: the neurobiology sector offers a complete research approach to understand the brain mechanisms and functions.

Our brain is made up of 100 billion nerve cells – each one connected to around 10.000 others. To understand this enormously complex structure, we need to investigate the properties of nerve cells and the way in which they encode and transmit information.

Neurobiologists seek to explain the mechanisms that account for behaviour and for cognitive higher functions in terms of sensory signals, integration and motor output.  The SISSA Neurobiology sector faces this challenge with an interdisciplinary approach, combining different research lines and closely working with physicists, mathematicians, nanotechnolgists and biologists.

From single molecules to synaptic plasticity, from sensory systems to advanced imaging techniques: all these fascinating research areas can be investigated in our labs in an original and fruitful way.

 

Research Fields

    • Olfactory Systems and Ion Channels
    • Applied Neurophysiology and Neuropharmacology
    • Bionanotechnology
    • New Materials and Neurons
    • Phototransduction
    • Structure and Function of Ionic Channels

 

Projects available for the first year students (Academic Year 2017-2018):

Vincent Torre
1. Ionic channels: electrophysiology and nanotechnology
2. Phototransduction


Anna Menini
1. Olfaction and smell


Laura Ballerini
1. Spinal synaptic activity in inflammation and disease
2. Nanotechnology and neuroscience
3. 3D artificial tissue constructs


Loredana Casalis
1. Extracellular nano and microvesicles in neurological disease progression
2. Design and fabrication of cell interactive 3D scaffolds
3. Miniaturized devices for circulating biomarkers assessment in neurodegenerative diseases


Dan Cojoc
1. Growth cone dynamics: optical manipulation and 3D imaging
2. Neuron signaling: optical manipulation and fluorescence imaging


Marco Lazzarino
1. Nanobiomechanics: cell adhesion, differentiation and mechanosensing
2. Brain cancer cell migration and nanomechanics investigated with atomic force microscopy 

 

 

 

Bionanotechnology and Neuroscience

Bionanotechnology and Neuroscience

New techniques developed in bionanotechnology, such as optical tweezers, are used to understand neuronal development.»

Spinal cord: circuits and regeneration

Spinal cord: circuits and regeneration

Spinal injury is produced by traumatic and nontraumatic causes that often induce long-term disability. This research ...»

 

Ion channels in health and disease

Ion channels in health and disease

Ion channels are key molecules for signal transduction across biological membranes. This research area explores the r...»

 

Synaptic Plasticity

Synaptic Plasticity

Combined electrophysiological, imaging and molecular biology approaches are used to study the molecular and cellular ...»

 

Advanced imaging

Advanced imaging

The aim of this research line is to develop new instrumentation and techniques for nanotechnology, biophysics and bio...»

Sensory Systems

Sensory Systems

This research line is interested in understanding how the brain represents the external world, working on the cellula...»

 
 
 

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