Research home

Michele Giugliano

Neuronal Dynamics Laboratory
From neurons to networks

Michele GiuglianoAssistant Professor

MG graduated in Electronic Engineering in 1997 at the University of Genova, Italy, and in 2001 received a PhD in Bioengineering and Computational Neuroscience from the Polytechnic of Milan, Italy. He was then awarded by the Human Frontiers Science Program Organisation with a long-term fellowship to pursue postdoctoral research in cellular electrophysiology at the Institute of Physiology of the University of Bern (Switzerland), working with Prof. Hans-Rudolf Luescher and Prof. Stefano Fusi. In 2005, he became junior group-leader in the experimental lab of Prof. Henry Markram at the Brain Mind Institute of the Swiss Federal Institute of Technology of Lausanne.

In 2008, he was appointed faculty at the University of Antwerp (Belgium) where he became full professor in 2016, taking over the Theoretical Neurobiology lab founded by Prof. Erik De Schutter and extending its scope to interdisciplinary research in experimental neuroscience and neuroengineering. During 2013-2015, he was visiting scientist at the Neuroelectronics Flanders Institute at IMEC, Leuven and also served other visiting academic positions at the Swiss Federal Institute of Technology of Lausanne and at the University of Sheffield, UK.

Since 2019, he has been Principal Investigator at SISSA and founder of the Neuronal Dynamics Laboratory.


MG's full CV is at


MG's lab website (in preparation) is at


Research Activities

The research interests of MG include

  • quantifying information processing and the response properties of cortical neurons;
  • investigating the impact of synaptic "noise" and ion channels "noise";
  • developing mathematical models of neurons and neuronal networks;
  • investigating heterogeneities in human and rodent cortical microcircuits;

My academic ResearchID and ORCID profiles are publicly accessible. 

Our PLoS Biology paper has been featured on Nature Podcast!


Internship, Theses, Monographic & PhD Projects


Lab Intro _008

A number of monographic projects and theses are available in the Neuronal Dynamics Laboratory, throughout each academic year. These are aimed at students of Life Sciences, Neuroscience, Physics, and Computer Sciences curricula, and cover topics of cellular electrophysiology, neurobiology, biophysics, theoretical and computational modelling and simulation, image processing, neuroinformatics, data-bases, robotics, analog-digital acquisition and real-time operating system. 

Interested? You are welcomed to get in touch for an appointment, to know more about our activities and about how you could contribute to it before, within, or beyond a master thesis project.

We are always searching for talented, curios, and passionate PhD students to train, as well as for creative thinkers and independent-minded postdoctoral researchers to collaborate with. In case of mutual interest, we help in preparing grant applications to national and international funding agencies such as JSPSHFSPOBoehringer IngelheimEC, and other sources. Students from Brazil may benefit from the Science Without Borders program, with application deadlines at the end of January, May and September. Students from China might monitor the calls from the China Scholarship Council.

In particular, potential postdoctoral scientists may wish to consider applying for support from Marie Curie Actions (deadline in August), HFSP (deadline in August), EMBO (deadlines in mid-February and mid-August).


Do you want to know more? Watch some YouTube videos of mine:









Selected publications

Cerebral Cortex, in press

Single-cell and neuronal network alterations in an in vitro model of Fragile X syndrome

 A. Moskalyuk, S. Van De Vijver, P. Verstraelen, W.H. De Dos, R.F. Kooy, and M. Giugliano.

PeerJ 7:e6796

The effect of pharmacological inhibition of Serine Proteases on neuronal networks in vitro.

Van De Vijver S, Missault S, Van Soom J, Van Der Veken P, Augustyns K, Joossens J, Dedeurwaerdere S, Giugliano M.

Front Neurosci. 2019 Jan 15;12:953. doi: 10.3389/fnins.2018.00953. eCollection 2018. Review. PubMed PMID: 30697140; PubMed Central PMCID: PMC6341218.

Advances in Nano Neuroscience: From Nanomaterials to Nanotools

Pampaloni NP, Giugliano M, Scaini D, Ballerini L, Rauti R.

Nature Communications 9: 4882

Locomotion modulates specific functional cell types in the mouse visual thalamus

Cagatay A, Couto J, Giugliano M, Farrow K, Bonin V

Cell Reports 23(9):2732-43

Human pluripotent stem cell-derived cortical neurons integrate functionally into the lesioned adult murine visual cortex in an area-specific way

Espuny-Camacho I, Michelsen KA, Linaro D, Bilheu A, Acosta-Verdugo S, Herpoel A, Giugliano M, Gaillard A, Vanderhaeghen P

European Journal of Neuroscience 47(1):17–32

Dynamical response properties of neocortical neurons to conductance‐driven time‐varying inputs

Linaro D, Biró I, Giugliano M

eLife 7:e41714

Large and fast human pyramidal neurons associate with intelligence

Goriounova NA, Heyer DB, Wilbers R, Verhoog MB, Giugliano M, Verbist C, Obermayer J, Kerkhofs A, Smeding H, Verberne M, Idema S, Baayen JC, Pieneman AW, de Kock CPJ, Klein M, Mansvelder HD.

Nat Nanotechnol. 2018 Aug;13(8):755-764. doi:10.1038/s41565-018-0163-6. Epub 2018 Jun 11. PubMed PMID: 29892019.

Single-layer graphene modulates neuronal communication and augments membrane ion currents

Pampaloni NP, Lottner M, Giugliano M, Matruglio A, D'Amico F, Prato M, Garrido JA, Ballerini L, Scaini D.

Scientific Reports vol. 6:24701

Brief wide-field photostimuli evoke and modulate oscillatory reverberating activity in cortical networks

Pulizzi R, Musumeci G, Van den Haute C, Van De Vijver S, Baekelandt V, Giugliano M 

Nature 522(7556):340-4

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

Peelaerts W, Bousset L, Van der Perren A, Moskalyuk A, Pulizzi R, Giugliano M, Van den Haute C, Melki R, Baekelandt V

Fundamental Biomedical Technologies 2012, 187-207

Carbon nanotubes as electrical interfaces to neurons

M. Giugliano, L. Gambazzi,  L. Ballerini, M. Prato, S. Campidelli.


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