Research home

Michele Giugliano

Neuronal Dynamics Laboratory
From neurons to networks

Michele GiuglianoAssistant Professor


Bio-sketch and CV

Lab website, publications, news, videos..


MG graduated in Electronic Engineering in 1997 at the University of Genova, Italy, and in 2001 received a PhD in Bioengineering and Computational Neuroscience from the Polytechnic of Milan, Italy. He was then awarded by the Human Frontiers Science Program Organisation with a long-term fellowship to pursue postdoctoral research in cellular electrophysiology at the Institute of Physiology of the University of Bern (Switzerland), working with Prof. Hans-Rudolf Luescher and Prof. Stefano Fusi. In 2005, he became junior group-leader in the experimental lab of Prof. Henry Markram at the Brain Mind Institute of the Swiss Federal Institute of Technology of Lausanne.

In 2008, he was appointed faculty at the University of Antwerp (Belgium) where he became full professor in 2016, taking over the Theoretical Neurobiology lab founded by Prof. Erik De Schutter and extending its scope to interdisciplinary research in experimental neuroscience and neuroengineering. During 2013-2015, he was visiting scientist at the Neuroelectronics Flanders Institute at IMEC, Leuven and also served other visiting academic positions at the Swiss Federal Institute of Technology of Lausanne and at the University of Sheffield, UK.

Since 2019, he has been Principal Investigator at SISSA and director of the Neuronal Dynamics Laboratory.



Research Activities

The research interests of MG include

  • quantifying information processing and the response properties of cortical neurons;
  • investigating the impact of synaptic "noise" and ion channels "noise";
  • developing mathematical models of neurons and neuronal networks;
  • investigating heterogeneities in human and rodent cortical microcircuits;

My academic ResearchID and ORCID profiles are publicly accessible. 

Our PLoS Biology paper has been featured on Nature Podcast!


Internship, Theses, Monographic & PhD Projects


Lab Intro _008

A number of monographic projects and theses are available in the Neuronal Dynamics Laboratory, throughout each academic year. These are aimed at students of Life Sciences, Neuroscience, Physics, and Computer Sciences curricula, and cover topics of cellular electrophysiology, neurobiology, biophysics, theoretical and computational modelling and simulation, image processing, neuroinformatics, data-bases, robotics, analog-digital acquisition and real-time operating system. 

Interested? You are welcomed to get in touch for an appointment, to know more about our activities and about how you could contribute to it before, within, or beyond a master thesis project.

We are always searching for talented, curios, and passionate PhD students to train, as well as for creative thinkers and independent-minded postdoctoral researchers to collaborate with. In case of mutual interest, we help in preparing grant applications to national and international funding agencies such as JSPSHFSPOBoehringer IngelheimEC, and other sources. Students from Brazil may benefit from the Science Without Borders program, with application deadlines at the end of January, May and September. Students from China might monitor the calls from the China Scholarship Council.

In particular, potential postdoctoral scientists may wish to consider applying for support from Marie Curie Actions (deadline in August), HFSP (deadline in August), EMBO (deadlines in mid-February and mid-August).

 Click here for our lab website, publications, news, videos..

Do you want to know more? Watch some YouTube videos of mine:









Selected publications

Front Cell Neurosci. 2020 Jun 17;14:118.

Homogeneous and Narrow Bandwidth of Spike Initiation in Rat L1 Cortical Interneurons

Borda Bossana S, Verbist C, Giugliano M.

iScience, Volume 23, Issue 10, 23 October 2020.

Plasticity and Adaptation in Neuromorphic Biohybrid Systems

George R, Chiappalone M, Giugliano M, Levi T, Vassanelli S, Partzsch J, Mayr C

Front Neurosci. 2020 May 19;14:405

Low-Impedance 3D PEDOT:PSS Ultramicroelectrodes

Jones PD, Moskalyuk A, Barthold C, Gutöhrlein K, Heusel G, Schröppel B, Samba R, Giugliano M

Mol Brain. 2020 May 19;13(1):78

Foetal neural progenitors contribute to postnatal circuits formation ex vivo: an electrophysiological investigation

Manzati M, Sorbo T, Giugliano M, Ballerini L

Cereb Cortex. 2020 Jan 10;30(1):31-46

Single-cell and neuronal network alterations in an in vitro model of Fragile X syndrome

A. Moskalyuk, S. Van De Vijver, P. Verstraelen, W.H. De Dos, R.F. Kooy, and M. Giugliano.

PLoS Comput Biol. 2020 Jul 23;16(7):e1008087

The location of the axon initial segment affects the bandwidth of spike initiation dynamics

Verbist C, Müller MG, Mansvelder HD, Legenstein R, Giugliano M

PeerJ 7:e6796

The effect of pharmacological inhibition of Serine Proteases on neuronal networks in vitro.

Van De Vijver S, Missault S, Van Soom J, Van Der Veken P, Augustyns K, Joossens J, Dedeurwaerdere S, Giugliano M.

eLife 7:e41714

Large and fast human pyramidal neurons associate with intelligence

Goriounova NA, Heyer DB, Wilbers R, Verhoog MB, Giugliano M, Verbist C, Obermayer J, Kerkhofs A, Smeding H, Verberne M, Idema S, Baayen JC, Pieneman AW, de Kock CPJ, Klein M, Mansvelder HD.

European Journal of Neuroscience 47(1):17–32

Dynamical response properties of neocortical neurons to conductance‐driven time‐varying inputs

Linaro D, Biró I, Giugliano M

Nat Nanotechnol. 2018 Aug;13(8):755-764.

Single-layer graphene modulates neuronal communication and augments membrane ion currents

Pampaloni NP, Lottner M, Giugliano M, Matruglio A, D'Amico F, Prato M, Garrido JA, Ballerini L, Scaini D.

Nature 522(7556):340-4

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

Peelaerts W, Bousset L, Van der Perren A, Moskalyuk A, Pulizzi R, Giugliano M, Van den Haute C, Melki R, Baekelandt V


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